上皮中性粒细胞活化肽78抗体说明书

中文名称  上皮中性粒细胞活化肽78抗体
英文名称  Anti-CXCL5
浓度  1mg/1ml
规格  0.1ml/100μg  0.2ml/200μg     
抗体来源  Rabbit  
克隆类型  polyclonal
交叉反应  Mouse, Rat,   
产品类型  上皮中性粒细胞活化肽78抗体一抗    
研究领域  免疫学 生长因子和激素  
蛋白分子量  predicted molecular weight: 8/9kDa
性状  Lyophilized or Liquid
免疫原  KLH conjugated synthetic peptide derived from mouse CXCL5 C-terminus
亚型  IgG
纯化方法  affinity purified by Protein A
储存液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用  WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500
（石蜡切片需做抗原修复）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍  The protein encoded by this gene is an inflammatory chemokine that belongs to the CXC chemokine family. This chemokine is produced concomitantly with interleukin-8 (IL8) in response to stimulation with either interleukin-1 (IL1) or tumor necrosis factor-alpha (TNFA). This chemokine is a potent chemotaxin involved in neutrophil activation. [provided by RefSeq].

Function : May participate in the recruitment of inflammatory cells by injured or infected tissue. GCP-2(1-78) and, more potent, GCP-2(9-78) attract neutrophils and are involved in neutrophil activation.
Subcellular Location : Secreted.

Post-translational modifications : GCP-2(1-78) and GCP-2(9-78) are produced by proteolytic cleavage after secretion from fibroblasts and epithelial cells. GCP-2(9-78) is the most prominent form. A number of additional N-terminal (processed between pos. 41 and 48) and C-terminal (processed between pos. 118 and 132) processed forms have been identified, probably also representing intermediate states.
Similarity : Belongs to the intercrine alpha (chemokine CxC) family.
Database links : UniProtKB/Swiss-Prot: P50228.2