DDRGK1蛋白抗体简介说明

英文名称  DDRGK1  
中文名称  DDRGK1蛋白抗体   
说 明 书  0.2ml   
研究领域  细胞生物 免疫学 神经生物学   
抗体来源  Rabbit  
克隆类型  Polyclonal  
交叉反应  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,  
产品应用  WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 DDRGK1蛋白抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.  
分 子 量  33kDa  
细胞定位  细胞浆  
性  状  Lyophilized or Liquid  
浓  度  1mg/1ml  
免 疫 原  KLH conjugated synthetic peptide derived from human DDRGK1  
亚  型  IgG  
纯化方法  affinity purified by Protein A  
储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4  
保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.  

DDRGK1蛋白抗体产品介绍  background:
DDRGK1 (DDRGK domain-containing protein 1), also known as C20orf116, is a 314 amino acid secreted protein. DDRGK1 contains one PCI domain and is expressed as two isoforms produced by alternative splicing. The gene that encodes DDRGK1 maps to human chromosome 20, which represents about 2% of human DNA and consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought to be important for seminal production. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20

Subcellular Location:
Endoplasmic reticulum

Tissue Specificity:
Ubiquitously expressed (at protein level).

Post-translational modifications:
Ufmylated. Conjugated to ubiquitin-like protein UFM1, probably at Lys-267. The role of ufmylation is unclear

Similarity:
Belongs to the DDRGK1 family
Contains 1 PCI domain

Database links:
UniProtKB/Swiss-Prot: Q96HY6.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.