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短链脱氢还原酶1抗体应用方法

219 人阅读发布时间:2022-03-15 16:13

产品名称:短链脱氢还原酶1抗体
别名:dehydrogenase/reductase (SDR family) member 1; Dehydrogenase/reductase SDR family member 1; FLJ25430; MGC20204; DHRS1_HUMAN. 
浓度:1mg/1ml 
规格:0.2ml/200μg          
抗体来源:Rabbit  
克隆类型:polyclonal 
交叉反应:Human, Mouse, Rat   
产品类型:短链脱氢还原酶1抗体一抗    
研究领域:心血管 细胞生物 免疫学  
蛋白分子量:predicted molecular weight: 34kDa 
性状:Lyophilized or Liquid 
免疫原:KLH conjugated synthetic peptide derived from human DHPS1 
亚型:IgG 
纯化方法:affinity purified by Protein A 
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
产品应用:WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 
(石蜡切片需做抗原修复) 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存条件:Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 . 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍:DHRS1 (dehydrogenase/reductase (SDR family) member 1), also known as SDR19C1, is a 313 amino acid protein that belongs to the short-chain dehydrogenases/reductases (SDR) family and likely functions as an oxidoreductase. Abundantly expressed in heart and liver, DHRS1 contains an SDR motif and is encoded by a gene that maps to human chromosome 14q12. Human chromosome 14 houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Tissue Specificity : Detected in heart and liver, and at low levels in skeletal muscle, kidney and pancreas. 
Similarity : Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Database links : UniProtKB/Swiss-Prot: Q96LJ7.1
 
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