硫酸软骨素蛋白多糖3抗体简介说明

英文名称    Epiphycan   

中文名称    硫酸软骨素蛋白多糖3抗体   

别    名    Dermatan sulfate proteoglycan 3; DSPG3; Epiphycan; epiphycan proteoglycan; EPYC; EPYC_HUMAN; Pg Lb; PG-Lb; PGLB; Proteoglycan-Lb; SLRR3B; Small chondroitin/dermatan sulfate proteoglycan.   

供 应 商   远慕生物

研究领域    发育生物学  干细胞  糖蛋白     

抗体来源    Rabbit   

克隆类型    Polyclonal   

交叉反应    Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,    

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 硫酸软骨素蛋白多糖3抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.   

分 子 量    35kDa   

细胞定位    细胞外基质 分泌型蛋白    

性    状    Lyophilized or Liquid   

浓    度    1mg/1ml   

免 疫 原    KLH conjugated synthetic peptide derived from human Epiphycan/DSPG3   

亚    型    IgG   

纯化方法    affinity purified by Protein A   

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4   

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.   

硫酸软骨素蛋白多糖3抗体产品介绍    background:

DSPG3 is a 322 amino acid secreted protein that belongs to the small leucine-rich proteoglycan (SLRP) family. Expressed in cartilage, ligament and placenta, DSPG3 may have a role in bone formation and in establishing the ordered structure of cartilage through matrix organization. It has been suggested that DSPG3 regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix proteins.

Function:
May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization.

Subcellular Location:
Secreted; extracellular space; extracellular matrix.

Tissue Specificity:
Cartilage, ligament, and placenta.

Post-translational modifications:
The O-linked polysaccharides on Thr-60 and Ser-96 are probably the mucin type linked to GalNAc. There is one glycosaminoglycan chain, known to be dermatan sulfate, and it is probably the O-glycosylation at Ser-64.

Similarity:
Belongs to the small leucine-rich proteoglycan (SLRP) family.
SLRP class III subfamily.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain.