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脑钠通道蛋白2抗体实验原理
人阅读 发布时间:2018-07-31 16:48
中文名称:脑钠通道蛋白2抗体
英文名: ACCN2 Antibody
供应商:乔羽生物
靶点: ACCN2
浓度: 1mg/ml
应用范围: WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500 ICC: 1:100-500 FC: 1:100-500
宿主: Rabbit
适应物种: Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, , Sheep
标记物: 无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
克隆性: 否
保存条件: 保存于-20℃
形态: 液态
亚型: Rabbit Polyclonal IgG
免疫原: Peptide derived from human ACCN2/ASIC1.
规格: 0.1ml
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from human ACCN2/ASIC1.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Acid sensing ion channel ASIC1 is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. In situ hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety. ASIC2, also designated amiloride-sensitive cation channel 1, neuronal (ACCN1), mammalian degenerin, BNAC1 (MDEG) and brain Na+ channel 1, mediates the normal detection of light touch. ASIC2 mRNA is abundant in brain, specifically in neurons. ASIC2 is expressed as 2.7- and 3.7-kb transcripts in brain and spinal cord tissues. ASIC3, also designated SLNAC1 and TNaC1, mediates detection of lasting pH changes and is involved in modulating moderate- to high-intensity pain sensation.
Alternate Names:
ASIC1; ACCN2; ACCN2_HUMAN; Acid sensing ion channel 1; Acid sensing ion channel 1a protein; Acid sensing ion channel; Acid-sensing ion channel 1; AI843610; Amiloride sensitive cation channel 2 neuronal; Amiloride-sensitive cation channel 2; ASIC; ASIC1; ASIC1A; BNAC2; Brain sodium channel 2; Cation channel amiloride sensitive neuronal 2; hBNaC2; neuronal.
Specificity Reaction:Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, , Sheep
Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500 ICC: 1:100-500 FC: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.